{"id":15768,"date":"2026-05-20T07:41:09","date_gmt":"2026-05-20T07:41:09","guid":{"rendered":"https:\/\/qalabs.medicasapp.com\/in\/?post_type=product&p=15768"},"modified":"2026-05-20T09:03:33","modified_gmt":"2026-05-20T09:03:33","slug":"hboc-comprehensive-panel-20-gene-hereditary-cancer-panel","status":"publish","type":"product","link":"https:\/\/qalabs.medicasapp.com\/in\/product\/hboc-comprehensive-panel-20-gene-hereditary-cancer-panel\/","title":{"rendered":"HBOC Comprehensive Panel (20-Gene Hereditary Cancer Panel)"},"content":{"rendered":"

The HBOC Comprehensive Panel is an advanced Next-Generation Sequencing (NGS)-based genetic test designed to identify inherited mutations associated with Hereditary Breast and Ovarian Cancer (HBOC) and related cancer syndromes. This expanded panel evaluates 20 clinically significant genes, including high-risk genes like BRCA1 gene, BRCA2 gene, and TP53 gene, along with moderate-risk genes such as ATM gene, CHEK2 gene, and PALB2 gene.<\/p>\n

This comprehensive cancer gene panel enhances genetic risk assessment, early cancer detection, and precision oncology treatment planning, making it ideal for individuals with complex personal or family cancer histories.\u00a0Non-fasting.<\/i><\/p>\n

Sample Required:<\/h3>\n

The HBOC Comprehensive Panel requires a blood sample, collected in an EDTA vacutainer (purple top). The sample must be transported under refrigerated conditions (2\u20138\u00b0C) within 72 hours.<\/p>\n

Test Time:<\/h3>\n

The test results are typically available within 12\u201314 days, depending on sequencing and reporting timelines.<\/p>\n

Test Normal Range:<\/h3>\n

The normal result is no pathogenic or likely pathogenic mutations detected in the tested genes.<\/p>\n

    \n
  • Negative: No clinically significant mutations identified<\/li>\n
  • Positive: Pathogenic mutation detected (increased cancer risk)<\/li>\n
  • VUS (Variant of Uncertain Significance): Requires expert genetic counseling<\/li>\n<\/ul>\n

    What is the test?<\/h3>\n

    The HBOC Comprehensive Panel is a broad-spectrum hereditary cancer genetic test that analyzes multiple genes associated with breast, ovarian, and related cancers. It is widely used in cancer genomics, precision medicine, and hereditary cancer screening programs.<\/p>\n

    This test helps:<\/p>\n

      \n
    • Identify high-risk and moderate-risk genetic mutations<\/li>\n
    • Enable personalized cancer treatment (targeted therapy, PARP inhibitors)<\/li>\n
    • Support preventive oncology and surveillance strategies<\/li>\n<\/ul>\n

      Test Procedure:<\/h3>\n

      A blood sample is collected and processed using high-depth NGS technology (~450x coverage). DNA is extracted and sequenced to detect mutations, insertions, deletions, and copy number variations across 20 genes. Results are interpreted by molecular geneticists and oncologists.<\/p>\n

      When to take the test?<\/h3>\n

      This test is recommended in the following scenarios:<\/p>\n

        \n
      • Personal or family history of multiple cancers<\/li>\n
      • Early-onset or bilateral breast cancer<\/li>\n
      • Individuals with two primary or recurrent cancers<\/li>\n
      • Before risk-reducing surgeries (mastectomy\/oophorectomy)<\/li>\n
      • For advanced cancer risk stratification and treatment planning<\/li>\n<\/ul>\n

        Who should take this test?<\/h3>\n
          \n
        • Individuals with complex hereditary cancer history<\/li>\n
        • Patients with aggressive or early-onset cancers<\/li>\n
        • Families with multiple cancer syndromes<\/li>\n
        • Individuals seeking comprehensive genomic cancer screening<\/li>\n
        • Patients planning precision oncology-based treatments<\/li>\n<\/ul>\n

          Precautions for exceptional cases (pregnancy etc.):<\/h3>\n

          Pregnant individuals or those with existing medical conditions should consult their healthcare provider before testing. Genetic counseling is strongly recommended before and after testing to understand medical and familial implications.<\/p>\n

          Genes Covered<\/h3>\n

          ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, NBN, NF1, PALB2, PMS2, PTEN, RAD51C, RAD51D, STK11, TP53<\/p>\n

          Indications for Testing<\/h3>\n
            \n
          • Personal or family history of multiple cancer types<\/li>\n
          • Early-onset or bilateral breast cancer<\/li>\n
          • Individuals with recurrent or multiple primary cancers<\/li>\n
          • Candidates for preventive surgeries<\/li>\n
          • Need for advanced genetic risk profiling<\/li>\n<\/ul>\n

            Inheritance Pattern<\/h3>\n

            Most genes in this panel follow an autosomal dominant inheritance pattern, while a few may have autosomal recessive inheritance:<\/p>\n

              \n
            • Increased cancer risk with a single mutated gene<\/li>\n
            • 50% inheritance risk for first-degree relatives<\/li>\n
            • Enables family-wide screening and preventive care<\/li>\n<\/ul>\n

              Why is This Test Important?<\/h3>\n

              The HBOC Comprehensive Panel enables:<\/p>\n

                \n
              • Comprehensive hereditary cancer risk assessment<\/li>\n
              • Personalized treatment planning and targeted therapy selection<\/li>\n
              • Identification of high-risk individuals for early intervention<\/li>\n
              • Better long-term outcomes through proactive cancer care<\/li>\n<\/ul>\n

                Applicable Cancers<\/h3>\n
                  \n
                • Hereditary Breast and Ovarian Cancer (HBOC)<\/li>\n
                • Breast Cancer<\/li>\n
                • Ovarian Cancer<\/li>\n
                • Prostate Cancer<\/li>\n
                • Pancreatic Cancer<\/li>\n
                • Endometrial Cancer<\/li>\n
                • Gastrointestinal Cancers (Lynch syndrome-related)<\/li>\n<\/ul>\n

                  Technical Information<\/h3>\n
                    \n
                  • Methodology: Next-Generation Sequencing (NGS)<\/li>\n
                  • Depth of Coverage: ~450x (high sensitivity and accuracy)<\/li>\n<\/ul>\n
                      \n
                    • HBOC comprehensive panel test Hyderabad | BRCA1 BRCA2 TP53 genetic testing Hyderabad<\/li>\n
                    • Cancer genetic testing Delhi NCR | hereditary cancer panel Delhi | NGS cancer test Delhi<\/li>\n
                    • BRCA gene test Bangalore | HBOC panel Bangalore | genomic cancer testing Bangalore<\/li>\n
                    • Breast cancer genetic test Chennai | BRCA screening Chennai | hereditary cancer testing Chennai<\/li>\n
                    • BRCA mutation test Mumbai | HBOC genetic panel Mumbai | cancer genomics Mumbai<\/li>\n
                    • Genetic cancer screening near me India | hereditary cancer test near me<\/li>\n
                    • NGS cancer panel India | DNA cancer test India | genomic profiling cancer India<\/li>\n
                    • Liquid biopsy test India | tumor marker test India | cancer biomarker testing India<\/li>\n
                    • Precision oncology India | targeted therapy testing India | PARP inhibitor eligibility test India<\/li>\n
                    • BRCA testing Secunderabad | genetic cancer test Hitech City Hyderabad<\/li>\n
                    • Cancer gene panel Gurgaon | BRCA test Noida | hereditary cancer screening Delhi NCR<\/li>\n
                    • BRCA panel Whitefield Bangalore | cancer gene test Electronic City Bangalore<\/li>\n
                    • Genetic testing T Nagar Chennai | BRCA test Anna Nagar Chennai<\/li>\n
                    • BRCA test Navi Mumbai | cancer gene panel Thane Mumbai<\/li>\n
                    • Genetic cancer testing Vizag | BRCA test Vijayawada | cancer screening Warangal<\/li>\n
                    • Genetic test Karimnagar | HBOC panel Tirupati | cancer gene test Guntur<\/li>\n
                    • BRCA test Coimbatore | genetic cancer screening Madurai<\/li>\n
                    • Cancer genetic testing Pune | BRCA panel Nagpur<\/li>\n
                    • BRCA test Jaipur | hereditary cancer screening Lucknow<\/li>\n
                    • Genetic testing Chandigarh | cancer gene panel Indore | BRCA test Bhopal<\/li>\n
                    • HBOC panel Surat | cancer genetic test Ahmedabad<\/li>\n
                    • BRCA testing Kochi | cancer gene test Trivandrum<\/li>\n
                    • Genetic cancer screening Patna | BRCA test Ranchi<\/li>\n
                    • Cancer genetic testing Guwahati | BRCA panel Bhubaneswar<\/li>\n
                    • Book cancer genetic test online India | home sample collection BRCA test India<\/li>\n
                    • Best cancer genetic labs India | affordable BRCA test India cost<\/li>\n
                    • Early cancer detection genetic test India | cancer risk assessment India<\/li>\n
                    • Advanced genomic testing India | hereditary cancer screening India<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

                      The HBOC Comprehensive Panel is an advanced Next-Generation Sequencing (NGS)-based genetic test designed to identify inherited mutations associated with Hereditary…<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"product_brand":[],"product_cat":[112],"product_tag":[],"class_list":["post-15768","product","type-product","status-publish","product_cat-cancer","first","instock","sale","shipping-taxable","purchasable","product-type-simple"],"acf":{"faqs":null},"yoast_head":"\n\n\n\n\n\n\n\n\n\n\n\n\t\n