Endometrial Cancer Focused Gene Panel with MSI

Description

(POLE, PTEN, TP53 whole gene sequencing with MSI by IHC)

Tissue, NA, Fasting or Non Fasting: As suggested by doctor

Sample Required:

FFPE endometrial tissue block OR fresh tissue in DCGL Preservative Solution at 2–8°C.

Test Time:

Biopsy-dependent. 8–12 working days.

Test Normal Range:

No fixed normal range.

What is the Test?

An extended panel assessing **POLE, PTEN, TP53** plus MSI evaluation using immunohistochemistry for mismatch repair proteins.

Test Procedure:

Tumour tissue undergoes NGS plus MSI IHC.

When to Take the Test:

When immunotherapy relevance and mutation profile are both required.

Who Should Take This Test:

Patients with endometrial cancer being evaluated for MSI-high status or targeted therapy.

Precautions for Exceptional Cases (Pregnancy, etc.):

Avoid biopsy during pregnancy unless medically necessary; ensure tissue meets tumour content requirement.